The draw was made at 12:00 CET on 25 February at the House of European Football in Nyon, Switzerland.

UEFA Europa League round of 16 draw

Rangers (SCO) vs Crvena zvezda (SRB)
Braga (POR) vs Monaco (FRA)
Porto (POR) vs Lyon (FRA)
Atalanta (ITA) vs Leverkusen (GER)
Sevilla (ESP) vs West Ham (ENG)
Barcelona (ESP) vs Galatasaray (TUR)
Leipzig (GER) vs Spartak Moskva (RUS)
Real Betis (ESP) vs Eintracht Frankfurt (GER)

The draw featured 16 teams:

• Eight group winners from the UEFA Europa League group stage
• Eight winners from the UEFA Europa League knockout round play-offs

Seeded teams

Crvena zvezda (SRB)
Eintracht Frankfurt (GER)
Galatasaray (TUR)
Leverkusen (GER)
Lyon (FRA)
Monaco (FRA)
Spartak Moskva (RUS)
West Ham (ENG)

Unseeded teams

Atalanta (ITA)
Barcelona (ESP)
Betis (ESP)
Braga (POR)
Leipzig (GER)
Porto (POR)
Rangers (SCO)
Sevilla (ESP)

How the draw worked

• The group winners were seeded and drawn against the winners of the knockout round play-offs.

• The UEFA Europa League group winners play the second leg at home.

• Clubs from the same association could not be drawn against each other.

Match dates

First legs: 9, 10 March
Second legs: 17 March

• Porto and Betis will play the first legs at home on Wednesday 9 March (kick-off 18:45 CET) to avoid a clash with Braga and Sevilla, repectively. The other first legs will take place on Thursday 10 March.